Scientific Tools Website

[Chibuike_Okechukwu]

Please, I need a website where I can download cracked scientific software like PyMOL or PyRx.
downloadly.ir is down.

[welcome_nightmare]

Can you describe more specific so i can help

[Chibuike_Okechukwu]

I need tools like PyMOL, PyRx, or ChemDraw or Schrodinger

[rmdn]

my go to for downloading sw check : filecr

[SRZ]

You Don’t Need Cracks. PyMOL & PyRx Are Already Free.

Plot twist: The software you’re hunting for has official free versions. Better than cracked. Zero malware. Zero “site is down” panic.

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What You’re Walking Away With

A complete cheat-sheet to get PyMOL, PyRx, and 100+ other molecular tools — all free, all legit, all with working download links.

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Why This Changes Everything

→ PyMOL’s source code is on GitHub. Schrödinger publishes it themselves.
→ PyRx has always had a free version on SourceForge. You just didn’t know.
→ You’ve been hunting cracks for software that was never actually locked.

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What You Get

• No malware — straight from the people who made it
• No “downloadly.ir is down” — these links don’t die
• Updates actually work — no broken installs
• University IT won’t flag you — fully legit
• Real support — forums and wikis that actually help

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START HERE — Your Exact Question Answered

PyMOL (Pick Whatever’s Easiest For You)

Method	Link	How Hard?
Windows Installer	github.com/cgohlke/pymol-open-source-wheels	Download → double-click → done
One Command	conda install -c conda-forge pymol-open-source	Need Anaconda first (get it here)
Student/Teacher	pymol.org/edu	.edu email = full paid version FREE
Build From Source	github.com/schrodinger/pymol-open-source	For nerds who like compiling

PyRx (Even Easier)

Method	Link	Notes
Free Version	sourceforge.net/projects/pyrx/files	Older but works perfectly
Official Site	pyrx.sourceforge.io	BSD license = open source
Pro (50% off)	pyrx.sourceforge.io	Use code ACADEMIC

That’s it. You’re done. Click, download, use. No cracks needed.

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Want More Free Stuff? Keep Scrolling.

Everything below is organized by what you’re trying to do — not random “tiers” that mean nothing.

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“I Need to SEE Molecules” (Visualization)

Free Molecular Viewers — Click to Expand

Software	Link	What It’s Good For
UCSF Chimera	cgl.ucsf.edu/chimera	The classic — everyone uses this
UCSF ChimeraX	cgl.ucsf.edu/chimerax	Newer, prettier graphics
VMD	ks.uiuc.edu/Research/vmd	Best for animations & movies
Avogadro 2	avogadro.cc	Easy molecule building
Jmol	jmol.sourceforge.net	Works in web browsers
VESTA	jp-minerals.org/vesta	Crystal structures
Discovery Studio Visualizer	discover.3ds.com	Free version from Dassault
Molden	theochem.ru.nl/molden	View Gaussian output files
MolView	molview.org	Works in your browser, zero install

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“I Need to DOCK Molecules” (Drug Discovery Stuff)

Free Docking Software — Download & Install

Software	Link	Why Use It
AutoDock Vina	github.com/ccsb-scripps/AutoDock-Vina	Industry standard, Apache license
AutoDock-GPU	github.com/ccsb-scripps/AutoDock-GPU	Same thing but uses your graphics card = faster
GNINA	github.com/gnina/gnina	AI-powered scoring
smina	sourceforge.net/projects/smina	Vina fork with custom scoring
rDock	rdock.github.io	Open source, good for virtual screening

Web Servers — Zero Install, Run in Browser

These run on someone else’s supercomputer. You just upload your files and wait.

Server	Link	What It Does
SwissDock	swissdock.ch	Small molecule docking
DockThor-VS	dockthor.lncc.br/v2	Virtual screening (runs on Brazilian supercomputer)
HADDOCK	rascar.science.uu.nl/haddock2.4	Protein-protein docking
HDOCK	hdock.phys.hust.edu.cn	Hybrid docking approach
Webina	durrantlab.pitt.edu/webina	Literally Vina running in your browser
CB-Dock2	clab.labshare.cn/cb-dock2	Auto-detects binding sites
MTiOpenScreen	bioserv.rpbs.univ-paris-diderot.fr/services/MTiOpenScreen	Screen 10,000 compounds

AI/ML Docking — The Cutting Edge Stuff

Tool	Link	What’s Special
DiffDock	github.com/gcorso/DiffDock	Uses diffusion models (like image AI)
DynamicBind	github.com/luwei0917/DynamicBind	Handles flexible proteins
NeuralPLexer	github.com/zrqiao/NeuralPLexer	Predicts structures
Uni-Mol	github.com/dptech-corp/Uni-Mol	Universal molecular AI
DeepChem	deepchem.io	ML toolkit for drug discovery

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“I Need QUANTUM CHEMISTRY” (Calculating Energies, Orbitals, etc.)

Free Quantum Chemistry Programs

What’s quantum chemistry? = Calculating how electrons behave in molecules. Used for reaction mechanisms, spectra prediction, etc.

Software	Link	Notes
ORCA	orcaforum.kofo.mpg.de	Register (free) → download. 100,000+ users. Best free option.
GAMESS	msg.chem.iastate.edu/gamess	Free academic, been around forever
NWChem	nwchemgit.github.io	Open source, DOE-funded
Psi4	psicode.org	Modern, Python-friendly
CP2K	cp2k.org	Materials science focused
Firefly	classic.chem.msu.su/gran/gamess	Russian GAMESS fork, very fast
Quantum ESPRESSO	quantum-espresso.org	Solid-state physics
GPAW	wiki.fysik.dtu.dk/gpaw	Python-based DFT

“But I want Gaussian!” → Gaussian is not free. But ORCA does 90% of the same stuff and IS free. Or check if your university has a site license (many do: Harvard, Cambridge, CMU, Stanford, etc.)

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“I Need MOLECULAR DYNAMICS” (Simulating Movement Over Time)

Free MD Software

What’s molecular dynamics? = Simulating how molecules move and wiggle over time. Used for protein folding, drug binding, etc.

Software	Link	Notes
GROMACS	gromacs.org	Industry standard, extremely fast
OpenMM	openmm.org	GPU-accelerated, Python API
NAMD	ks.uiuc.edu/Research/namd	Handles millions of atoms
LAMMPS	lammps.org	Materials + molecules
AMBER (Tools)	ambermd.org	AmberTools is free
Tinker	dasher.wustl.edu/tinker	Force field development
OpenMD	github.com/OpenMD/OpenMD	Lipids, metals, nanoparticles

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“I Need CHEMINFORMATICS” (Working with Chemical Data)

Free Chemistry Toolkits

What’s cheminformatics? = Programming with molecules. Converting file formats, calculating properties, filtering databases, etc.

Library	Link	Notes
RDKit	rdkit.org	Industry standard, Python/C++
OpenBabel	openbabel.org	Convert ANY file format to ANY other
CDK	cdk.github.io	Java-based
Indigo	github.com/epam/Indigo	EPAM’s toolkit

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“Just Give Me an Installer” (DDL Sites)

Don’t want to think? These sites have direct download links:

Site	Link	What’s There
GetIntoPC	getintopc.com	Gaussian 16, GaussView, scientific suites
FileCR	filecr.com	Schrödinger Suite 2025-3, Maestro
ChemistWizards	chemistwizards.com	PyMOL, Gaussian guides + downloads
Softonic	pymol.en.softonic.com	PyMOL
SourceForge	sourceforge.net	PyRx, PyMOL, many others

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“I Have a University Email” (Academic Freebies)

Free Stuff for Students/Researchers

Your .edu email unlocks a lot:

Software	Link	What You Get
PyMOL	pymol.org/edu	Full paid version, free
Schrödinger Suite	schrodinger.com/academics	Maestro + everything
ORCA	orcaforum.kofo.mpg.de	Register with academic email
ChemAxon	chemaxon.com	Request free academic license
SBGrid	sbgrid.org	500+ apps if your lab is a member
Gaussian	Ask your university IT	Many have site licenses

SBGrid Consortium — The Academic Jackpot

If your lab is a member (500+ labs in 23 countries), you get:

What	Link
Main Site	sbgrid.org
Software List	sbgrid.org/software
Schrödinger Access	sbgrid.org/software/titles/schrodinger
ORCA Access	sbgrid.org/software/titles/orca
Chimera Access	sbgrid.org/software/titles/chimera

Harvard Medical School runs it. Includes Schrödinger tokens (normally $$$).

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“I Need More Computing Power” (Free Supercomputer Access)

Run Heavy Calculations for Free

Your laptop too slow? Use someone else’s supercomputer:

Platform	Link	Who Can Use
ACCESS-CI	access-ci.org	US researchers (free allocation)
Google Colab	colab.research.google.com	Anyone (free GPU)
DockThor HPC	dockthor.lncc.br	Anyone (Brazilian supercomputer)
CSC Finland	docs.csc.fi	Finnish/EU academics
NERSC	nersc.gov	DOE-funded research
Ohio Supercomputer	osc.edu	Ohio academics
ARCHER2 (UK)	archer2.ac.uk	UK academics

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“I Don’t Want to Install Anything” (Browser-Based)

Everything Runs in Your Browser

Tool	Link	What It Does
MolView	molview.org	3D molecule viewer
Webina	durrantlab.pitt.edu/webina	Docking in browser
SwissDock	swissdock.ch	Docking server
3Dmol.js	3dmol.csb.pitt.edu	WebGL viewer
AlphaFold	alphafold.ebi.ac.uk	Protein structure prediction
Swiss-Model	swissmodel.expasy.org	Homology modeling
I-TASSER	zhanggroup.org/I-TASSER	Structure prediction
Robetta	robetta.bakerlab.org	Structure prediction

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Mega-Lists (Curated by Researchers)

Other people already made giant lists of free tools:

List	Link	What’s Inside
Open Source Molecular Modeling	opensourcemolecularmodeling.github.io	200+ tools, reviewed
awesome-cheminformatics	github.com/hsiaoyi0504/awesome-cheminformatics	GitHub mega-list
awesome-drug-discovery	github.com/yboulaamane/awesome-drug-discovery	Databases + ML + courses
awesome-python-chemistry	github.com/lmmentel/awesome-python-chemistry	Python packages
CACHE Teaching Resources	cache.org/teaching-resources-center/molecular-modeling	Academic toolkit
MolSSI	molssi.org	NIH-funded development
CCS-Psi	ccs-psi.org/software/mms	DOE exascale tools

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“I Need to LEARN This Stuff” (Tutorials)

Free Courses & Tutorials

Resource	Link	What You Learn
TeachOpenCADD	github.com/volkamerlab/teachopencadd	Drug design from scratch
Practical Cheminformatics	github.com/PatWalters/practical_cheminformatics_tutorials	ML, clustering, real workflows
drugdesign.org	drugdesign.org	Free drug design courses
RSC CICAG YouTube	youtube.com/c/RSCCICAG	20+ video workshops
Omics Tutorials	omicstutorials.com	PyRx docking guides

PyMOL Specifically

Resource	Link
PyMOL Wiki	pymolwiki.org
Pymol-script-repo	github.com/Pymol-Scripts/Pymol-script-repo
MooersLab Shortcuts	github.com/MooersLab/pymolshortcuts
MooersLab EasyPyMOL	github.com/MooersLab/EasyPyMOL
MooersLab Snippets	github.com/MooersLab/pymolsnips
BCRF UW-Madison	bcrf.biochem.wisc.edu/pymol-resources
PyMOL Mailing List	sourceforge.net/p/pymol/mailman/pymol-users
PyVibMS Plugin	github.com/smutao/PyVibMS

Blogs Worth Following

Blog	Link	Focus
Practical Cheminformatics	practicalcheminformatics.blogspot.com	ML + drug discovery
MacinChem	macinchem.org	macOS chemistry tools
Silico Studio	silicostudio.com	Free tool guides
BioPchem	biopchem.education	Teaching resources

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Regional Sources (Country-Specific)

Non-English Resources

Region	Platform	Link	Content
Russia	Firefly	classic.chem.msu.su/gran/gamess	Fast QM package
China	CSDN	blog.csdn.net (search: PyMOL安装)	Tutorials, installers
China	Novopro 纽普生物	novopro.cn	PyMOL wheels
Japan	YoshitakaMo	github.com/YoshitakaMo/pymolplugin	Restored PyMOL plugins
Brazil	DockThor	dockthor.lncc.br/v2	Free HPC docking
Spain	BIO-HPC	github.com/bio-hpc/metascreener	Docking pipeline

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Christoph Gohlke — The Windows Wizard

This guy at UC Irvine has been compiling Windows installers for Python packages since 2009. Legend.

Resource	Link
Main Site	cgohlke.com
GitHub	github.com/cgohlke
PyMOL Wheels	github.com/cgohlke/pymol-open-source-wheels
Geospatial Wheels	github.com/cgohlke/geospatial-wheels

Python Software Foundation Fellow 2019. Community Service Award 2014. Trusted for 15+ years.

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“I Need Help” (Communities)

Forums, Discord, Slack

Community	Platform	Link
ORCA Forum	Web	orcaforum.kofo.mpg.de
PyMOL Mailing List	Email	sourceforge.net/p/pymol/mailman/pymol-users
BIO-HPC	Discord	bio-hpc.eu
Bioinformatics	Discord	discord.gg/3uxbPns
Chemistry	Discord	discord.gg/chemistry
r/bioinformatics	Slack	DM u/apfejes on Reddit
BioBit	Chat	bit.bioinf.me
Life Science Training	Slack	jasonjwilliamsny.github.io/LifeSciTrainingSlack
Bioconductor	Zulip	bioconductor.zulipchat.com
AutoDock List	Email	autodock.scripps.edu

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“I Need Papers/Textbooks” (Shadow Libraries)

This is for papers and books, not software:

Platform	Link	Content
Anna’s Archive	annas-archive.li	51M+ books, 98M+ papers
Nexus Project	Telegram: @nexus_search_3_bot	Latest papers
Library Genesis	libgen.is / libgen.rs	33M+ items
Sci-Hub	scihub.help	85M+ articles
r/Scholar	reddit.com/r/Scholar	Request papers
Internet Archive	archive.org	Historical + books

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Copy-Paste Setup (For the Impatient)

# Install Anaconda first: https://www.anaconda.com/download

# Then run this:
conda create -n compchem python=3.11
conda activate compchem
conda install -c conda-forge pymol-open-source autodock-vina rdkit openbabel

# Done. You now have PyMOL + Vina + chemistry toolkit.

PyRx: Just download from SourceForge.

ORCA: Register at orcaforum.kofo.mpg.de, download same day.

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Why Cracked Sites Are Now Pointless

Fact	Proof
PyMOL is open source	github.com/schrodinger/pymol-open-source
PyRx is free	sourceforge.net/projects/pyrx/files
ORCA is free (academic)	orcaforum.kofo.mpg.de
Web servers exist	SwissDock, DockThor, Webina — zero install
Universities have licenses	Ask your IT department
Open-source alternatives beat commercial	GNINA, DiffDock, VirtualFlow

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Stop hunting for .ir mirrors. The software you need was free this whole time — you just didn’t know where to look.

Now you do.

[Chibuike_Okechukwu]

IN Source Forge, it is version 0.8, and it has been updated to 1.2. This is not in SourceForge